The author performed a clinical study of 295 patients with alopecia areata in order to evaluate the clinical manifestations and the effects of treatment with intralesional injection of triamcinolone acetonide suspension and immunotherapy with
diphenylcyclopropenone(DPCP) from March, 1992 to February, 1994 at the Department of Dermatology, College of Medicine, Chung Ang University.
@ES The results were follows:
@EN 1) The age distribution showed a peak incidence in the third decade(38.6%0 and average age was 28.6 years.
2) The most common site of predilection was occipital region in both male and female, which were 83 cases(60.2%), 74 cases(59.2%) respectively.
3) The relapse rate was 26.8%).
4) The family histories were contributory in 34 cases(11.5%).
5) Associated diseases with alopecia areata were seborrheic dermatitis, hepatitis, atopic dermatitis, thyroid diseases, vitiligo, hypertension, pulmonary diseases, etc.
6) The therapeutic effect in cases of balded area less than 45cm*, treated with intralesional injection of triamcinolone acetonide revealed less effective according to increase the size of balded area.
7) In cases of balded area more than 46cm*, alopecia totalis and alopecia universalis, 18 cases of the 30 cases(60%) treated with intralesional injection of triamcinolone acetonide revealed effective and 24 cases of the 37 cases(64.9%) treated
with
immunotherapy with DPCP revealed slightly more effective.
These findings suggested that alopecia areata was prominantly developed in third decade, and showed good therapeutic effect in cases of balded area less than 5cm* and relatively good therapeutic effect on the group treated with DPCP than
intralesional
injection of triamcinolone acetonide in cases of balded area more than 46cm*, alopecia totalis and alopecia universalis.
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